This report summarizes efforts to explore whether water efficiency efforts can be linked in practice to improved instream flows in areas of the Colorado River basin. In brief, we found that practical possibilities to do this do exist within the current context of the river basin. Given a stream stretch with a clearly identified need for improved instream flows and a realistic opportunity for improving water efficiency, willing partners generally can build the bridges needed to overcome other challenges. The landing page for this report also includes a PDF of a webinar on the topic and additional resources.